Description
5-Amino-1MQ
Chemical Information:
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Molecular Formula: C₇H₁₁N₅
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Molecular Weight: 165.20 g/mol
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Chemical Name: 5-Amino-1-methylquinolin-1-ium
Description:
5-Amino-1MQ is a small-molecule experimental compound that functions as a methyltransferase inhibitor, particularly targeting nicotinamide N-methyltransferase (NNMT). This enzyme plays a role in regulating cellular energy metabolism, making 5-Amino-1MQ a focus of research into obesity, metabolic disorders, and age-related energy decline. By modulating NNMT activity, 5-Amino-1MQ may influence NAD⁺ levels and energy balance in experimental models.
Storage and Handling:
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Store sealed at recommended laboratory freezer temperatures.
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Protect from light, moisture, and excessive heat.
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Handle using standard laboratory safety procedures to maintain product integrity.
Product Specifications:
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Purity: ≥99% (HPLC Verified)
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Appearance: Orange lyophilized powder
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Solubility: Refer to Certificate of Analysis for physicochemical properties
Important Note:
For Research Use Only – Not for Human or Veterinary Use
This product is intended strictly for in vitro research and laboratory experimentation by qualified professionals. It is not a drug, food, cosmetic, or dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease. The bodily introduction of this product into humans or animals is strictly prohibited by law. Any misuse, misbranding, or mislabeling of this product is a violation of federal regulations.
References:
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Kraus, D., et al. (2014). “Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity.” Nature
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Hong, S., et al. (2018). “NNMT Inhibitors as a Therapeutic Option for Metabolic Disorders.” Journal of Medicinal Chemistry
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Policarpo, R., et al. (2020). “Development of Potent NNMT Inhibitors for Modulating Energy Metabolism.” ACS Medicinal Chemistry Letters
